8 Tweets Feb 04, 2023
1/ Gooood morning, #MedTwitter! It’s time for another round of #12LeadThursday.
Remember to approach every ECG systematically. Use your system now - this 43 y/o patient had a cardiac arrest in the field and this is his EKG post-ROSC.
What’s going on?
2/ Yes, yikes indeed. Now, let’s say you’re at a facility without PCI capability, and you can’t get the patient to one within 2 hours.
Now what do you do?
3/ Fibrinolytics are old, and they work; this meta-analysis suggests the totality of the evidence has favored their use since the 1970s (jamanetwork.com).
Once you get the fibrinolytics going, what else will you be giving your patient?
4/ It’s all of the usual suspects! We’re talking loading doses of dual antiplatelet therapy as well as starting anticoagulation.
5/ Your patient’s chest pain resolves, and this is his follow-up ECG 90 minutes after initiating your therapeutic cocktail.
Your work here isn’t finished, so we’ll ask again: now what?
6/ Regardless of whether medical therapy was successful, your patient still needs a PCI and you should be transferring them while fibrinolytics are still running.
7/ Be sure to check out this week’s post and all our previous #12LeadThursday content on our website: coreimpodcast.com
8/ In summary: if PCI can’t be performed within 2 hours, patients with STEMIs get fibrinolytics in addition to DAPT and anticoagulation. They still need PCI, and should be transferred to the nearest PCI-capable facility ASAP.

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