Weekend Digest
A boy from Indiana has fevers, chills, and erythematous macular rash.
Exposure: pet rat.
Blood cultures +. Gram stain of the growth (photo): tangled chains of pleomorphic GNB, some with central bulbar swelling.
Name the disease, its pathogen and Rx.
A boy from Indiana has fevers, chills, and erythematous macular rash.
Exposure: pet rat.
Blood cultures +. Gram stain of the growth (photo): tangled chains of pleomorphic GNB, some with central bulbar swelling.
Name the disease, its pathogen and Rx.
2/
#RatBiteFever #Haverhill Fever
Causes
1. S. moniliformis (North America)
2. S. notomytis (Japan)
3. Spirillum minus (Asia) #sodoku
Note: blood culture with GNR:
S. minus is uncultivable, a distinguishing feature from Streptobacillus spp.
doi.org
#RatBiteFever #Haverhill Fever
Causes
1. S. moniliformis (North America)
2. S. notomytis (Japan)
3. Spirillum minus (Asia) #sodoku
Note: blood culture with GNR:
S. minus is uncultivable, a distinguishing feature from Streptobacillus spp.
doi.org
3/
#RatBite #Haverhill Fever
Rodents - Streptobacillus / Spirillum are part of normal flora
Asymptomatic carriage of S. moniliformis among rats is very common: wild rats (50-100%), laboratory rats (10-100%)
Also: mice, guinea pigs, gerbils, squirrels
jcm.asm.org
#RatBite #Haverhill Fever
Rodents - Streptobacillus / Spirillum are part of normal flora
Asymptomatic carriage of S. moniliformis among rats is very common: wild rats (50-100%), laboratory rats (10-100%)
Also: mice, guinea pigs, gerbils, squirrels
jcm.asm.org
4/
#RatBiteFever
Saliva / secretions of rodents contain #Streptobacillus - transmitted by:
1. Bite / scratch
2. Saliva
3. Urine
4. Feces / droppings
Food and drink contaminated by rat secretions β> #Haverhill Fever
cdc.gov
#RatBiteFever
Saliva / secretions of rodents contain #Streptobacillus - transmitted by:
1. Bite / scratch
2. Saliva
3. Urine
4. Feces / droppings
Food and drink contaminated by rat secretions β> #Haverhill Fever
cdc.gov
/5
#IDDailyPearl #RatBiteFever #Haverhill
1. Rodents.
2. #Streptobacillus. #Spirillum (Asia).
3. Bite. Scratch. Secretions. Droppings.
4. Fever. Arthrlagias. Rash.
5. Penicillin. Ceftriaxone. Doxycycline (if betalactam allergic)
#IDDailyPearl #RatBiteFever #Haverhill
1. Rodents.
2. #Streptobacillus. #Spirillum (Asia).
3. Bite. Scratch. Secretions. Droppings.
4. Fever. Arthrlagias. Rash.
5. Penicillin. Ceftriaxone. Doxycycline (if betalactam allergic)
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