#Tweetorial on the new updated @AmerGastroAssn Guidelines in @AGA_Gastro on #IBS below ππΎ
All βοΈ Guideline Panel: @LinChangMD @AnthonyLemboMD @SultanShazi @jheidel Walter Smalley & Nicholas Verne
More info: ow.ly
All βοΈ Guideline Panel: @LinChangMD @AnthonyLemboMD @SultanShazi @jheidel Walter Smalley & Nicholas Verne
More info: ow.ly
Core components for all patients with IBS:
πΈ strong pt-provider relationship
πΈ education & reassurance
πΈdietary modifications (e.g. low FODMAP diet)
πΈ lifestyle modifications (exercise, sleep, β¬οΈ stress)
πΈ strong pt-provider relationship
πΈ education & reassurance
πΈdietary modifications (e.g. low FODMAP diet)
πΈ lifestyle modifications (exercise, sleep, β¬οΈ stress)
Pharm mgmt of pts with IBS (regardless of type):
β antispasmodics for abdominal pain
β TCAs (8 RCTs with clinically meaningful β¬οΈ in global sx)
β SSRIs (7 RCTs: no sig β¬οΈ global sx or abd pain)
*Note that these are conditional recommendations with low certainty in evidence*
β antispasmodics for abdominal pain
β TCAs (8 RCTs with clinically meaningful β¬οΈ in global sx)
β SSRIs (7 RCTs: no sig β¬οΈ global sx or abd pain)
*Note that these are conditional recommendations with low certainty in evidence*
.@AmerGastroAssn Guideline on IBS-Diarrhea:
β eluxadoline (do not use in pts with no GB or EtOH >3x/d)
β rifaximin, incl re-tx in those with recurrent sx after initial response
β alosetron
*conditional recs w/moderate certainty in evidence*
β loperamide (w/very low certainty)
β eluxadoline (do not use in pts with no GB or EtOH >3x/d)
β rifaximin, incl re-tx in those with recurrent sx after initial response
β alosetron
*conditional recs w/moderate certainty in evidence*
β loperamide (w/very low certainty)
.@AmerGastroAssn Guideline on IBS-Constipation:
β Linaclotide (linzess)- Strong Rec/High Qual Evid
And conditional recs & moderate evid for:
β Tenapanor (ibsrela)
β Plecanatide (trulance)
β Lubiprostone (amitiza)
β Tegaserod β‘οΈ re-approved for women <65yo w/o hx CV events
β Linaclotide (linzess)- Strong Rec/High Qual Evid
And conditional recs & moderate evid for:
β Tenapanor (ibsrela)
β Plecanatide (trulance)
β Lubiprostone (amitiza)
β Tegaserod β‘οΈ re-approved for women <65yo w/o hx CV events
For pts with persistent #IBS sx despite above therapy, the @AmerGastroAssn Clinical Decision Support Tool calls for considering:
πΈadding or switching to a low dose TCA
πΈSNRI
πΈBrain-Gut Behavior Therapy incl CBT and hypnosis
πΈadding or switching to a low dose TCA
πΈSNRI
πΈBrain-Gut Behavior Therapy incl CBT and hypnosis
Don't miss the opportunity to hear directly from the @AGA_Gastro authors! @LinChangMD @AnthonyLemboMD @SultanShazi @jheidel Walter Smalley & Nicholas Verne
Join our Gastro Bites webinars on
πΉJuly 7 at noon EDT
πΉJuly 21 at noon EDT
Register here: ow.ly
Join our Gastro Bites webinars on
πΉJuly 7 at noon EDT
πΉJuly 21 at noon EDT
Register here: ow.ly
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