Nick Mark MD
Nick Mark MD

@nickmmark

4 Tweets Dec 27, 2022
I've been thinking about #PhysicsInTheICU: physical laws/principles with clear clinical correlates:
Hagen–Poiseuille --> fluid resuscitation
Ohm's --> SVR from CO & MAP/CVP
Reynold’s --> Heliox w/ airway obstruction
Fick's --> Resorption atelectasis, N2 washout in PTX
Others?
There are a whole lot with ultrasound:
Nyquist
Doppler
Bernoulli
Continuity equation etc
Time constant on a ventilator is analogous to an RC circuit.
(For the 3 other people on 🌎 who like electrical analogies to explain pulmonary physiology…)
TC (τ) = R x C
Normal TC = 0.5 to 0.7 sec
Factors that increase resistance (R) & compliance (C) will prolong exhalation
Laplace —> aortic aneurysms & atelectasis

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