Cell Therapy Engineering:
I wanted to do my Cell Engineering sector report, but I think I want to prefix that will this thread first. I have done threads in the past for the cell therapies space covering the history of cell therapies.
I wanted to do my Cell Engineering sector report, but I think I want to prefix that will this thread first. I have done threads in the past for the cell therapies space covering the history of cell therapies.
1/ I even did some threads on the applications of cell engineering.
2/ This continues part 2 of my cell engineering threads.
3/ This is part 3 of my cell engineering thread.
4/ Now that I laid out the ideas of Cell Engineering, I want to look at Induced Pluripotent Stem Cells (iPSC) and why I think they will revolutionize the world of cell engineering.
5/ #1 Immortality
Stem cells are immortal. They can reproduce over and over again without limit. This makes them the perfect source for cell therapies independent of any donor or patient.
Stem cells are immortal. They can reproduce over and over again without limit. This makes them the perfect source for cell therapies independent of any donor or patient.
6/ #2 Endless Editing
Because a stem cell is immortal, it can be edited endless amounts of time to engineer very complex cells with many attributes. There only needs to be one stem cell that gets all the necessary edits for it to become a starting source.
Because a stem cell is immortal, it can be edited endless amounts of time to engineer very complex cells with many attributes. There only needs to be one stem cell that gets all the necessary edits for it to become a starting source.
7/ #3 Easy Manufacturing
Many cell therapies require complex editing. It takes time to take cells from one person, edit them and match them to a patient who needs them. Stem cells can be manufactured in batches in reactors where they can yield thousands of doses.
Many cell therapies require complex editing. It takes time to take cells from one person, edit them and match them to a patient who needs them. Stem cells can be manufactured in batches in reactors where they can yield thousands of doses.
8/ #4 Accuracy
All cells as they grow and replicate can undergo spontaneous mutations. That is part of biology. With stem cell manufacturing, you have near perfect cells. Most batches of cells yield extremely high quality compared to trying to edit billions of cells.
All cells as they grow and replicate can undergo spontaneous mutations. That is part of biology. With stem cell manufacturing, you have near perfect cells. Most batches of cells yield extremely high quality compared to trying to edit billions of cells.
9/ #5 Unlimited Potential
Stem cells can become any cell in the body. We can use a combination of growth factors and gene editing to guide them down a path to development where they can become any cell we desire. This opens up many possibilities.
Stem cells can become any cell in the body. We can use a combination of growth factors and gene editing to guide them down a path to development where they can become any cell we desire. This opens up many possibilities.
10/ These are the reasons why I think that Stem Cell manufacturing of cells will become the monoclonal antibody of the Cell Therapy revolution. It offers a cost effective way to mass produce cell therapies.
11/ Next I want to look at the companies in the Cell Therapy report that are focused on cell engineering. Mostly around T cells and NK cells for cancer.
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