3/10
1 tweet methods
✅ 39 centers in United Kingdom.
✅ Adults (> 18 yo) with eGFR < 30 cc/min (CKD 4-5). Decrease of > 2 ml/min eGFR in previous 2 years.
✅ 411 patients followed every 3 months for 3 years, randomized 1:1.
1 tweet methods
✅ 39 centers in United Kingdom.
✅ Adults (> 18 yo) with eGFR < 30 cc/min (CKD 4-5). Decrease of > 2 ml/min eGFR in previous 2 years.
✅ 411 patients followed every 3 months for 3 years, randomized 1:1.
4/10
1 tweet results
🔹 1° outcome: eGFR 12.6 +/- 0.7 in discontinue vs 13.3 +/- 0.6 in continue group (p= 0.42)
🔹 2° outcome: ESKD/RRT in 62% of discontinue vs 56% in continue group (HR 1.28, 95% CI 0.99-1.65)
🔹 Serious adverse events were similar between the 2 groups.
1 tweet results
🔹 1° outcome: eGFR 12.6 +/- 0.7 in discontinue vs 13.3 +/- 0.6 in continue group (p= 0.42)
🔹 2° outcome: ESKD/RRT in 62% of discontinue vs 56% in continue group (HR 1.28, 95% CI 0.99-1.65)
🔹 Serious adverse events were similar between the 2 groups.
5/10
A figure paints 1000 words
A figure paints 1000 words
7/10
Chat consensus?
“For those already keeping pts on RASi they will keep doing it. For those who stopped due to fear of hastening KRT, [they] may change practice. Doesn’t change anything beyond that. CV benefit being underpowered and buried is a bummer.” @captainchloride
Chat consensus?
“For those already keeping pts on RASi they will keep doing it. For those who stopped due to fear of hastening KRT, [they] may change practice. Doesn’t change anything beyond that. CV benefit being underpowered and buried is a bummer.” @captainchloride
9/10
I want more info
✅ Check out this tweetorial from Dr Nayan Arora:
✅ Summary from @thana_susan: nephjc.com
✅ VA by @dana_m_larsen: nephjc.com
I want more info
✅ Check out this tweetorial from Dr Nayan Arora:
✅ Summary from @thana_susan: nephjc.com
✅ VA by @dana_m_larsen: nephjc.com
10/10
Final thoughts
✳️ This has been @brian_rifkin taking over for @jamiewillows. #TenTweetsNephJC.
He was a little busy, be sure to congratulate him on the birth of his new child!!
➡️ Up next - Dec 6, 7 Aprocitentan in Resistant HTN PRECISION in Lancet) !
@ChristosArgyrop
Final thoughts
✳️ This has been @brian_rifkin taking over for @jamiewillows. #TenTweetsNephJC.
He was a little busy, be sure to congratulate him on the birth of his new child!!
➡️ Up next - Dec 6, 7 Aprocitentan in Resistant HTN PRECISION in Lancet) !
@ChristosArgyrop
Loading suggestions...