Zaven Sargsyan
Zaven Sargsyan

@sargsyanz

4 Tweets Jan 17, 2023
@davserantes @ASanchez_PS @AnnKumfer @rabihmgeha @DxRxEdu Great question and thanks for the tag. This variability is seen everywhere in the literature, when evaluating other diagnostics (and therapeutics) too.
And itโ€™s all about what was the context, design, and people (both patients and providers) of the study.
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@davserantes @ASanchez_PS @AnnKumfer @rabihmgeha @DxRxEdu I try to get a sense of the *range* of test characteristics (TC) for a given diagnostics, then think about what elements of the technique, patient characteristics, or other contextual factors influence the TC, improve those elements that are modifiable, andโ€ฆ
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@davserantes @ASanchez_PS @AnnKumfer @rabihmgeha @DxRxEdu โ€ฆestimate where, within (or outside) the range of the reported TC, my finding in a particular case may sit.
Itโ€™s not necessarily, or even usually, quantitative.. just a ballpark.
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@davserantes @ASanchez_PS @AnnKumfer @rabihmgeha @DxRxEdu You might enjoy this ๐Ÿ‘‡๐Ÿผ. DM me if you canโ€™t access.
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