5 Tweets 20 reads Dec 23, 2022
An 18-year-old man presented with a 2-day history of fever, vomiting, and diarrhea.
Three weeks before presentation, he had fallen into a canal
What is the most likely diagnosis?
Physical exam was notable for the findings shown in the image.
Laboratory studies showed acute kidney injury and elevations in aminotransferase and total bilirubin levels.
Empirical treatment with intravenous penicillin was initiated.
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Serum nucleic acid amplification testing identified leptospira species of the serogroup icterohaemorrhagiae.
Leptospirosis manifesting as fever, jaundice, renal failure, and hemorrhage was suspected on the basis of
πŸ‘‰the patient’s classic presentations
πŸ‘‰ (including the subconjunctival bleeding)
πŸ‘‰ exposure to water with probable contamination by rodent urine.

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