Dr Sudhir Kumar MD DM
Dr Sudhir Kumar MD DM

@hyderabaddoctor

8 Tweets Feb 20, 2023
Consider lead toxicity due to Ayurvedic medications in patients with unexplained abdominal pain
1. In the past 6 months, we saw 5 patients with unexplained abdominal pain associated with weakness of hands and feet. All were taking Ayurvedic medicines for various reasons.
2. Blood lead levels were high in all of them (>25 mcg/dl). There was no history of occupational lead exposure in any of them.
They were treated with d-penicillamine (chelation therapy). Ayurvedic medicines were stopped.
#MedTwitter #NeuroTwitter #ayurvedicmedicine
3. Abdominal pain resolved. Weakness of hands and legs partially improved. Four patients had anemia and one had kidney damage (these showed only partial improvement).
4. About 9.3 % of patients with unexplained abdominal #pain are due to lead intoxication caused by taking Ayurvedic drugs.
doi.org
5. Ayurvedic medicine Jambrulin caused lead toxicity in a 58-year old woman, leading to abdominal pain, anemia and deranged liver function tests.
doi.org
6. Lead encephalopathy as a result of long-term ayurvedic medication intake can cause headache, #memory loss, confusion and worsening of sensorium. MRI brain shows damage and swelling (in basal ganglia and cerebral cortex) in these cases.
doi.org
7. Lead was found in 65% of 252 Ayurvedic medicine samples tested. 36% of samples had concentrations of lead per pill that exceeded, up to several thousand times, the recommended daily intake values for pharmaceutical impurities.
doi.org
8. Take home message
In patients with unexplained abdominal pain, anemia, memory loss, peripheral neuropathy or kidney damage, consider lead toxicity and enquire about Ayurvedic medicine intake.

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