Q: After how long PTT can be checked if Protamine is given for Heparin reversal?
Answer: About 5 - 15 minutes
It is recommended to check PTT in 6 hours again due to possibility of Heparin rebound phenomenon.
Dosage for heparin reversal is 0.5mg to 1.0 mg mg protamine sulfate IV for every 100 IU of active heparin.
Partial thromboplastin time (PTT) should be monitored at 5 to 15 minutes after dose then in 2–8 hours afterward.
Partial thromboplastin time (PTT) should be monitored at 5 to 15 minutes after dose then in 2–8 hours afterward.
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