Mayo Clinic Infectious Diseases
Mayo Clinic Infectious Diseases

@MayoClinicINFD

4 Tweets 1 reads Apr 22, 2023
#MayoIDCase #IDBR #MayoIDQ
You are consulted on a 45 man with diabetes who was admitted for back pain, fever, chills. CT showed thoracic vertebral osteomyelitis. Blood culture: #Trueperella pyogenes.
What is his most likely exposure or occupation?
2/
#GPB in spine biopsy culture was identified as #Trueperella pyogenes (previously known as Actinomyces / Arcanobacterium / Bacillus / Corynebacterium pyogenes)
High degree of bacteremia: TEE negative for vegetations
Rx with IV ceftriaxone x 6 weeks
3/
#Trueperella pyogenes is not part of human flora. It is in animals!
⁃Commensal in skin/GI/GU/respiratory tract of animals (cattle, goat, pig, sheep)
⁃Mastitis, abscesses, endometritis in animals
Risk: animal contact (MCQ answer: cattle farming)
ncbi.nlm.nih.gov
4/
#Trueperella pyogenes in humans
⁃Not a human commensal
⁃Zoonotic: exposure to animals and their environment (suggested MCQ answer: cattle farming)
⁃Sporadic reports of bacteremia, abscesses, endocarditis, endemic leg ulcers in humans
pubmed.ncbi.nlm.nih.gov

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