7 Tweets 4 reads Jan 29, 2023
A 52-year-old woman
πŸ‘‰ a 24-hour history of severe pain and blurred vision in the left eye
What is the likely diagnosis?
Acute conjunctivitis
Acute angle-closure glaucoma
Acute orbital compartment syndrome
Ulcerative keratitis
Vitreous hemorrhage
πŸ‘‰ described the pain as constant with a shooting character, lasting a few seconds
πŸ‘‰ examination of her lt eye revealed
πŸ‘‰ mid-dilated pupil that was unresponsive to light
πŸ‘‰ redness of the conjunctiva
πŸ‘‰ hardening of the left orbit on palpation
πŸ‘‰ VA 20/125 in the lt eye
An increased intraocular pressure of 55 mm Hg (normal range, 10 to 21) confirmed the diagnosis of acute angle-closure glaucoma,
πŸ‘‰an ophthalmologic emergency that is characterized by
πŸ‘‰ rapid increase in intraocular pressure due to impaired outflow of aqueous humor
Symptoms can be precipitated by
πŸ‘‰dim light
πŸ‘‰ certain medications, including anticholinergic and sympathomimetic drugs
πŸ‘‰ no history of taking these medications nor was any other cause identified
πŸ‘‰ treated with
πŸ‘‰intravenous acetazolamide
πŸ‘‰ a topical carbonic anhydrase inhibitor
πŸ‘‰ an Ξ±2-adrenergic agonist
πŸ‘‰ underwent laser iridotomy
πŸ‘‰after which her symptoms rapidly resolved
When she was discharged 4 hours later, the intraocular pressure was 10 mm Hg.
Subsequently, the patient was lost to long-term follow-up.
Acute angle-closure glaucoma
nejm.org
Acute angle-closure glaucoma
emnote.org

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