Poor sleep quality and sleeping <7 hours during adolescence can increase the risk of multiple sclerosis later in life
1. A recent case control study done at Sweden looked at the association between sleep duration (& quality) in teens and risk of multiple sclerosis in later life.
1. A recent case control study done at Sweden looked at the association between sleep duration (& quality) in teens and risk of multiple sclerosis in later life.
2. Compared with sleeping 7–9 hours/night during adolescence, short sleep (<7 hours/night) was associated with 40% increased risk of developing multiple sclerosis (MS).
3. When patients rated their sleep quality during adolescence as poor, the risk of developing MS in later life increased by 50%.
4. Conclusion
Insufficient sleep duration and poor sleep quality during adolescence can significantly increase the risk of developing MS in later life.
dx.doi.org
Insufficient sleep duration and poor sleep quality during adolescence can significantly increase the risk of developing MS in later life.
dx.doi.org
5a. Possible mechanisms of sleep deprivation and MS
*Insufficient sleep may contribute to the risk of inflammatory chronic diseases.
*Sleep restriction and poor sleep quality affect immune pathways with increased proinflammatory signaling, which could increase the risk of MS.
*Insufficient sleep may contribute to the risk of inflammatory chronic diseases.
*Sleep restriction and poor sleep quality affect immune pathways with increased proinflammatory signaling, which could increase the risk of MS.
5b. Circadian rhythms are also involved in regulating the immune response and disruption may result in disturbed melatonin secretion and immune dysfunction.
#MedTwitter #neurotwitter #MultipleSclerosis
#MedTwitter #neurotwitter #MultipleSclerosis
Adolescents should be encouraged to sleep well at nights (7-9 hours) to reduce the risk of developing multiple sclerosis and other inflammatory diseases (in later life).
Loading suggestions...