What if I told you there were a drug that could halt/reverse CTE and Alzheimer's?
What if I told you that drug could reverse stroke damage?
Cerebrolysin is that
Thread below
👇
What if I told you that drug could reverse stroke damage?
Cerebrolysin is that
Thread below
👇
Quick disclaimer
This is educational only. I am not making any recommendations
Do not ask me how to get it or how much to take
This will also be a BRIEF summary as this thread will be long enough as is
This is educational only. I am not making any recommendations
Do not ask me how to get it or how much to take
This will also be a BRIEF summary as this thread will be long enough as is
Cerebrolysin is a neuropeptide that improves the brain's ability for self-repair by stimulating neuro recovery.
It has numerous pharmacological effects, which will be listed below
It has numerous pharmacological effects, which will be listed below
Pharmacological effects:
- Protection against excitotoxicity
- Reduction of free radicals
- Reduction of pro-apoptotic enzymes
- Modulation of inflammatory effect
- Protection against excitotoxicity
- Reduction of free radicals
- Reduction of pro-apoptotic enzymes
- Modulation of inflammatory effect
Pharmacological effects cont.
- Improvement of BBB integrity
- Neuroplasticity
- Neurogenesis
- Reduction of post stroke dementia
- Improvement of BBB integrity
- Neuroplasticity
- Neurogenesis
- Reduction of post stroke dementia
Protection against excitotoxicity
-Overstimulation by L-glutamate damages neurons
-Cerebrolysin inhibits this
-Overstimulation by L-glutamate damages neurons
-Cerebrolysin inhibits this
Reduction of free radicals
-Free radicals are involved heavily in Alzheimer's and strokes
-Cerebrolysin is shown to greatly reduce the formation of free radicals following an ischemic event
-Free radicals are involved heavily in Alzheimer's and strokes
-Cerebrolysin is shown to greatly reduce the formation of free radicals following an ischemic event
Reduction of pro-apoptotic enzymes
-Apoptosis is cell death
-Cerebrolysin reduces the number of neurons capable of this
-Apoptosis is cell death
-Cerebrolysin reduces the number of neurons capable of this
Modulation of inflammatory effect
-Blood clots that lead to stroke cause the endothelial cells to become inflammatory
-Cerebrolysin reduces the cytokine storm that causes this
-Blood clots that lead to stroke cause the endothelial cells to become inflammatory
-Cerebrolysin reduces the cytokine storm that causes this
Improvement of BBB integrity
-The blood brain barrier is damaged by fibrin deposits and loses permeability
-Cerebrolysin improves the BBB by promoting vascular integrity via Ang1, VEGF, and SHH
-The blood brain barrier is damaged by fibrin deposits and loses permeability
-Cerebrolysin improves the BBB by promoting vascular integrity via Ang1, VEGF, and SHH
Ang1 (angiopoietin 1) promotes blood vessel remodeling and maturation
VEGF (vascular endothelial growth factor) promotes blood vessel formation
They both do a bit of each but this is good enough of a generalization for now
SHH will be addressed a bit further down
VEGF (vascular endothelial growth factor) promotes blood vessel formation
They both do a bit of each but this is good enough of a generalization for now
SHH will be addressed a bit further down
Improves Neuroplasticity
-Neuroplasticity is simply the ability of the brain to rewire itself in response to new demand
-Cerebrolysin increases the number of new synapses
-Neuroplasticity is simply the ability of the brain to rewire itself in response to new demand
-Cerebrolysin increases the number of new synapses
Neurogenesis
-Ischemic strokes cause neurons to deteriorate as well as blood vessel atrophy
-Cerebrolysin stimulates neurovascular growth and repair
-Ischemic strokes cause neurons to deteriorate as well as blood vessel atrophy
-Cerebrolysin stimulates neurovascular growth and repair
Reduction of post stroke dementia
-After a stroke, the blood clot breaks up and can lead to mini clots downstream in smaller vessels, continuing the release of cytokines
-Cerebrolysin restores normal blood flow through the mechanisms mentioned above
-After a stroke, the blood clot breaks up and can lead to mini clots downstream in smaller vessels, continuing the release of cytokines
-Cerebrolysin restores normal blood flow through the mechanisms mentioned above
Cerebrolysin modifies two major signaling pathways:
1. The neurotrophic factor (NTF)
2. Sonic hedgehog (SHH) signaling pathways
These both maintain and repair the neuronal network
1. The neurotrophic factor (NTF)
2. Sonic hedgehog (SHH) signaling pathways
These both maintain and repair the neuronal network
Neurotrophic factor:
-Maintain, protect and restore neural network
-Ensure proper brain function
-Survival and regeneration of the neuronal
network
-Maintain, protect and restore neural network
-Ensure proper brain function
-Survival and regeneration of the neuronal
network
Sonic hedgehog signaling pathways:
-Regulates the development of organs including the organization of the brain
-Amplifies recovery of neurons
-Regulates the development of organs including the organization of the brain
-Amplifies recovery of neurons
I say all of this to sum up as follows:
Cerebrolysin improves the ability of the brain to recover by stimulating neuro recovery across many pathways
Cerebrolysin improves the ability of the brain to recover by stimulating neuro recovery across many pathways
That's it.
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If you found this thread helpful:
1. Follow me @bowtiedkobra for more
2. RT the tweet below to share this thread
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