♨️#NephTwitter Residents
Suggesting again
“7 point differential assessment” for
💥AKI in Pregnancy (1/6)
1️⃣Period of gestation
2️⃣Prodromal symptom
3️⃣Coagulopathy
4️⃣LFT
5️⃣Platelets
6️⃣Hemolysis evidence
7️⃣Hypertension
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#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls
Suggesting again
“7 point differential assessment” for
💥AKI in Pregnancy (1/6)
1️⃣Period of gestation
2️⃣Prodromal symptom
3️⃣Coagulopathy
4️⃣LFT
5️⃣Platelets
6️⃣Hemolysis evidence
7️⃣Hypertension
Unroll...
#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls
♨️AKI in Pregnancy (2/6)
💥AFLP
1️⃣>34 Week
2️⃣Vomiting
3️⃣only in severe cases
4️⃣Jaundice
5️⃣Normal platelet
6️⃣Hemolysis absent
7️⃣Hypertension absent
🔆Polyuria‼️ d/t 🚫hepatic metabolism of placental Vasopressinase
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#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls
💥AFLP
1️⃣>34 Week
2️⃣Vomiting
3️⃣only in severe cases
4️⃣Jaundice
5️⃣Normal platelet
6️⃣Hemolysis absent
7️⃣Hypertension absent
🔆Polyuria‼️ d/t 🚫hepatic metabolism of placental Vasopressinase
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#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls
♨️AKI in Pregnancy (3/6)
💥HELLP
1️⃣Mostly 1st 48 hr postpartum
2️⃣severe pre-eclampsia
3️⃣20% cases
4️⃣SGOT/PT⬆️
5️⃣Plt< 100,000
6️⃣LDH>600
7️⃣Severe HTN
⚠️Also has ⬇️ADAMTS13 level‼️
🔆Variable degree renal failure
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#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls
💥HELLP
1️⃣Mostly 1st 48 hr postpartum
2️⃣severe pre-eclampsia
3️⃣20% cases
4️⃣SGOT/PT⬆️
5️⃣Plt< 100,000
6️⃣LDH>600
7️⃣Severe HTN
⚠️Also has ⬇️ADAMTS13 level‼️
🔆Variable degree renal failure
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#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls
♨️AKI in Pregnancy (4/6)
💥TTP
1️⃣Average 26wk
2️⃣Pentad (remember❓)
3️⃣None‼️
4️⃣LFT normal‼️
5️⃣Profound thrombocytopenia
6️⃣+
7️⃣+
⚠️Hallmark of TTP/HUS- Normal coagulation
🔆ADAMTS13 severely⬇️(<5%)
🔆AKI in 30-80%
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#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls
💥TTP
1️⃣Average 26wk
2️⃣Pentad (remember❓)
3️⃣None‼️
4️⃣LFT normal‼️
5️⃣Profound thrombocytopenia
6️⃣+
7️⃣+
⚠️Hallmark of TTP/HUS- Normal coagulation
🔆ADAMTS13 severely⬇️(<5%)
🔆AKI in 30-80%
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#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls
♨️AKI in Pregnancy (5/6)
💥HUS
1️⃣70% postpartum‼️
2️⃣Uremia
3️⃣None
4️⃣LFT normal
5️⃣Profound thrombocytopenia
6️⃣+
7️⃣+
⚠️Placental expression of complement regulatory protein protective in prepartum
🔆Predominant AKI
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#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls
💥HUS
1️⃣70% postpartum‼️
2️⃣Uremia
3️⃣None
4️⃣LFT normal
5️⃣Profound thrombocytopenia
6️⃣+
7️⃣+
⚠️Placental expression of complement regulatory protein protective in prepartum
🔆Predominant AKI
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#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls
♨️AKI in Pregnancy (6/6)
💥Acute Cortical Necrosis
1️⃣Usually postpartum
2️⃣Gross hematuria👉Anuria
3️⃣Consumptive if DIC
4️⃣Normal
5️⃣If DIC⬇️
6️⃣Absent
7️⃣Absent
⚠️Initiating event- DIC/ Severe renal ischemia
#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls #medicine #Medical
💥Acute Cortical Necrosis
1️⃣Usually postpartum
2️⃣Gross hematuria👉Anuria
3️⃣Consumptive if DIC
4️⃣Normal
5️⃣If DIC⬇️
6️⃣Absent
7️⃣Absent
⚠️Initiating event- DIC/ Severe renal ischemia
#NephroNotes #FOAMed #MedTwitter #MedEd #NephPearls #medicine #Medical
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