🦠Gut microbiome, inflammation🚨 and pain 😫management in ortho 🦴
I’m glad that this subject is making it into mainstream ortho literature and commend the authors from @MUHealthOrtho for their work.
Here’s my review of this review article for you to review 🧵 👇🏻#OrthoTwitter
I’m glad that this subject is making it into mainstream ortho literature and commend the authors from @MUHealthOrtho for their work.
Here’s my review of this review article for you to review 🧵 👇🏻#OrthoTwitter
The authors discuss various benefits of prebiotics & probiotics as well as supplements for osteoarthritis (OA), osteoporosis, fracture healing, rheumatoid arthritis (RA), and chemotherapy-induced arthralgia (joint pain)
🚨Important to note: These interventions may work, but they are no substitute to fixing your diet by eating wholesome foods🚨
The general principle is basically appreciating that pathogens and their metabolites in the gut can lead to ⬆️gut permeability (“leaky gut”) with a subsequent inflammatory immune response
Let’s start with osteoarthritis (OA)
Lactobacillus casei has been found to be helpful in ⬇️pain & ha-CRP (inflammation marker) in a placebo-controlled, double-blinded RCT
Freeze-dried strawberries 🍓, blueberries 🫐 have also been found helpful in OA in RCTs
Lactobacillus casei has been found to be helpful in ⬇️pain & ha-CRP (inflammation marker) in a placebo-controlled, double-blinded RCT
Freeze-dried strawberries 🍓, blueberries 🫐 have also been found helpful in OA in RCTs
Other supplements helpful in OA include green mussel extract, turmeric & curcumin, and garlic 🧄
Next, RA…
Next, RA…
In Rheumatoid Arthritis (RA), omega-3 supplements (flaxseed & fish🐟 oils) have been found helpful in ⬇️inflammation. Others include sesamin (derived from sesame), saffron, and garlic 🧄
Keep in mind, most n-3 supplements are oxidized. Eat the real thing (fatty, cold 🌊 wild 🐟)
Keep in mind, most n-3 supplements are oxidized. Eat the real thing (fatty, cold 🌊 wild 🐟)
Also helpful in RA, a Cretan Mediterranean diet is helpful when compared to a Westen diet
This diet is high-vegetable, incl 🫒 but ⬇️carb than a Western diet. Keep in mind, just about anything is better than a Western diet, so this is not a hit against a clean, animal-based diet
This diet is high-vegetable, incl 🫒 but ⬇️carb than a Western diet. Keep in mind, just about anything is better than a Western diet, so this is not a hit against a clean, animal-based diet
In RA, probiotics that ⬇️lab-measured inflammation but not necessarily patient-reported symptoms include Bifidobacterium bífidus, B coagulants, and various Lactobacillus spp.
Next, osteoporosis and fractures 🦴…
Next, osteoporosis and fractures 🦴…
In osteoporosis and fracture prevention, it’s best to start with strong bones 🦴
Corn 🌽 fiber, oligosaccharides, & inulin helped young women 🚺⬆️calcium absorption. Inulin-type fructans also showed ⬆️Bone Mineral Density in adolescents
Corn 🌽 fiber, oligosaccharides, & inulin helped young women 🚺⬆️calcium absorption. Inulin-type fructans also showed ⬆️Bone Mineral Density in adolescents
In elderly 🚺 Lactobacillus reuteri was found to markedly reduce bone 🦴 loss in the tibia.
Three Lactobacillus strains helped reduce bone 🦴 loss in spine
Bacillus subtilis resulted in ⬆️ BMD in the hip
Three Lactobacillus strains helped reduce bone 🦴 loss in spine
Bacillus subtilis resulted in ⬆️ BMD in the hip
For fracture healing, those with a single rib 🩻fracture had better pain reduction at 1 month with Lactobacillus casei.
In distal radius fractures… see tweet below 👇🏻
Finally, in cancer…
In distal radius fractures… see tweet below 👇🏻
Finally, in cancer…
For patients with breast cancer suffering from chemotherapy-induced joint pain, tart cherry 🍒 juice was found to be helpful in a double-blind RCT with ⬇️ pain by ⅓
Take care of your gut! Chronic orthopedic conditions are tied to diet much more than we ever have been made to believe. Thanks for reading
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