Welcome to #TenTweetNephJC
To salt or not to salt? 🧂 That is the question in heart failure💔
✳️ 10 tweets #NephJC catch-up ✳️
Missed the SODIUM-HF trial discussed last week? Read on for a snapshot of this RCT of dietary sodium reduction in patients with heart failure!
To salt or not to salt? 🧂 That is the question in heart failure💔
✳️ 10 tweets #NephJC catch-up ✳️
Missed the SODIUM-HF trial discussed last week? Read on for a snapshot of this RCT of dietary sodium reduction in patients with heart failure!
2/10
What did I miss?
Studies have shown inconsistent results of the effect of dietary sodium restriction. Now, we finally have better RCT evidence.
SODIUM-HF = adults with NYHA class 2-3 & on optimum medical therapy randomised to usual care or a low sodium diet (<1500mg/day)
What did I miss?
Studies have shown inconsistent results of the effect of dietary sodium restriction. Now, we finally have better RCT evidence.
SODIUM-HF = adults with NYHA class 2-3 & on optimum medical therapy randomised to usual care or a low sodium diet (<1500mg/day)
3/10
1 tweet methods
✅ Open-label, pragmatic, RCT
✅ Intervention group received a diet plan & behavioural counselling by trained professionals
✅ Primary outcome: composite of cardiovascular related hospitalisation, ED visits & all cause mortality within 12 months
1 tweet methods
✅ Open-label, pragmatic, RCT
✅ Intervention group received a diet plan & behavioural counselling by trained professionals
✅ Primary outcome: composite of cardiovascular related hospitalisation, ED visits & all cause mortality within 12 months
4/10
1 tweet results
🔹 n=397 in low Na group, n=409 in usual care group
🔹 Primary outcome occurred in 15% of patients in low Na group & 17% of patients with usual care (HR 0.89, p=0.53)
🔹 Subgroup analysis found ⬆️quality of life & ⬆️one NYHA class in intervention group
1 tweet results
🔹 n=397 in low Na group, n=409 in usual care group
🔹 Primary outcome occurred in 15% of patients in low Na group & 17% of patients with usual care (HR 0.89, p=0.53)
🔹 Subgroup analysis found ⬆️quality of life & ⬆️one NYHA class in intervention group
5/10
A figure paints 1000 words
A figure paints 1000 words
6/10
Give me something clever to say
“Because the degree of dietary sodium reduction that would lead to a reduction in clinical events has not yet been defined, the pros and cons of dietary intervention of salt intake should be considered on an individual basis”
Give me something clever to say
“Because the degree of dietary sodium reduction that would lead to a reduction in clinical events has not yet been defined, the pros and cons of dietary intervention of salt intake should be considered on an individual basis”
7/10
Chat consensus?
👍 Baseline Na consumption was generally low in both groups (~2g), is this representative of real life?
👎 No results on the use of diuretics in the patients
👉 Cardiologists & the @thelancet: 100mmol and 1500mg of Na is NOT the same
Chat consensus?
👍 Baseline Na consumption was generally low in both groups (~2g), is this representative of real life?
👎 No results on the use of diuretics in the patients
👉 Cardiologists & the @thelancet: 100mmol and 1500mg of Na is NOT the same
9/10
I want more info
✅ Follow @bilalksheikh & @williamvasesp
✅ Summary from @bilalksheikh
nephjc.com
✅ VA by @williamvasesp
I want more info
✅ Follow @bilalksheikh & @williamvasesp
✅ Summary from @bilalksheikh
nephjc.com
✅ VA by @williamvasesp
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