Dr Sudhir Kumar MD DM
Dr Sudhir Kumar MD DM

@hyderabaddoctor

9 Tweets 16 reads Jan 26, 2023
Daily coffee consumption is good for chronic liver disease patients
1. Coffee is a popular beverage & is known to have multiple health-related benefits including better overall survival in several diseases. A systematic review looked at association of coffee and #liver disease.
2. Coffee consumption was associated with improved serum gamma glutamyl transferase (GGT), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) values in a dose dependent manner in individuals at risk for liver disease.
#MedTwitter
3. In chronic liver disease patients who consume coffee, a decreased risk of progression to cirrhosis, a lowered death rate in cirrhosis patients, and a lowered rate of hepatocellular carcinoma (liver cancer) development were observed.
4. In chronic hepatitis C patients, coffee was associated with improved virologic responses to antiviral therapy.
Moreover, coffee consumption was inversely related to the severity of steatohepatitis in patients with non-alcoholic fatty liver disease (NAFLD).
7. Moderate coffee consumption has beneficial effects on various liver diseases, possibly by inhibiting adenosine binding to its receptors.
doi.org
8. Caffeine inhibits hepatic stellate cell activation by blocking adenosine receptors.
Caffeine favorably impacts angiogenesis and hepatic hemodynamics.
Chlorogenic acids (phenolic component of coffee) suppress liver fibrogenesis and carcinogenesis
doi.org
9. Take home message
Coffee consumption has favorable effects on liver diseases and people suffering from liver diseases should be encourage to consume coffee on daily basis.

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