Chris Masterjohn
Chris Masterjohn

@ChrisMasterjohn

7 Tweets 17 reads Feb 25, 2023
Nitric oxide is a signaling compound, which is meant to have highly controllable, fleeting effects. You’d be much better off nourishing it’s synthesis than using a drug to impair its breakdown.
2-10 grams of citrulline per day will increase circulating arginine levels, which is the amino acid that donates the nitrogen to make nitric oxide.
Zinc, sulfur, and BH4 are necessary cofactors of nitric oxide synthase.
Best sources of zinc are oysters, red meat, and cheese.
Best sources of sulfur are proteins, with eggs milk and meat providing double what plant proteins provide.
BH4 is made endogenously using zinc, magnesium, potassium, and niacin.
Theoretically high-dose folate (milligrams) could hurt BH4 synthesis and recycling because they both use the DHFR enzyme.
Magnesium is easiest to get from a broad range of unrefined plant foods. The easiest way to become deficient in magnesium is to eat the standard American diet based on white flour and sugar.
Potassium is needed in large quantities that don’t fit in one banana or in your multivitamin. Your whole diet needs to be geared towards getting enough.
Fruits and vegetables, legumes, tubers, and the lean portions of animal foods are all good sources of potassium.
Grains are not good sources, but whole grains are ok and refined grains are miserable.
On carnivore, emphasizing lean portions and retaining the juices of cooking helps keep potassium up.
On keto, emphasizing veggies with high potassium to net carb ratios helps.

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