1/4 ERYTHROMELALGIA I saw a case recently of a 33 yo M with a long history of recurrent pain, swelling, redness of feet > hands induced by heat, lasting 30-60 min, & relieved with cold. More recently, he has also developed cold-induced tricolor changes in his fingers.
2/4 Adjusting temperature for one symptom induces the other. He has found a "sweet spot" between 65-72 degrees F (ideally 69 degrees F). Physical exam normal, as was his CBC. ANA negative. This is most certainly a case of concomitant primary erythromelalgia and Raynaud's.
3/4 Learning points about erythromelalgia: 1. Associated with pain, redness, and warmth
2. Involves feet more than hands
3. Precipitated by warm/hot
4. Relieved with cold
5. Pathogenesis unknown - maybe hyperemia
6. May be primary or secondary
7. Treatment is unsatisfactory
4/4 Check out the accurate description of erythromelalgia from a paper published in 1891, just 17 years after the syndrome was first reported.