William Aird
Professor of Medicine at Harvard Medical School #Hematology #MedEd Founder of @TheBloodProjec1
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1/2 HYPERSPLENISM AND ANEMIA The idea that hypersplenism causes pancytopenia (a common claim) makes no physiological sense. Yes, it may lead to low platelets because TPO produc...
CASE STUDY 1/11 74 yo F presents with CBC shown in graphic below. You will note she has macrocytic anemia, which has a wide differential diagnosis (also shown in graphic). https:...
1/5 I saw my umpteenth patient with post-bariatric surgery and iron deficiency (ID) last week and realized it was time to brush up on the topic. A) DEFINITIONS: Bariatric surge...
1/9 @jlberrymd #b12deficiency Here's a cool case with an important take-home message. A 48 yo M is referred to you with macrocytic anemia. Before looking at the graphic you sho...
1/5 What is the difference between ERYTHROCYTOSIS and POLYCYTHEMIA? Although the terms are often used interchangeably, they have slightly different meanings. https://t.co/5fjWaS5...
1/4 #GI #GIbleed #urea Elevated BUN: creatinine ratio favors UPPER over lower GI bleed. Why? 1) Hb in stomach --> amino acids (aa). 2) aa absorbed by small intestine. 3) aa tr...
1/5 Diagnostic flow chart for hemolysis (see graphic) NOTES: 1. Immune (DAT+) or non-immune (DAT-)? 2. If immune (DAT is positive), allo or auto? What is the identify of the a...
1/6 POLYCLONAL GAMMOPATHY I was recently referred a patient for evaluation of polyclonal gammopathy. I have to admit that beyond liver disease and general inflammation, I was d...
1/4 HYPERSPLENISM History: First described by Wiseman and Doan in 1942 Definition: A syndrome characterized by: 1. Splenomegaly 2. Blood cytopenia(s) 3. Compensatory hyper...
#thyroid #endocrine 1/4 THYROID AND HEME 1. Thyroid and RBCs We often order a TSH as part of the w/u for anemia. But do we really understand the connection between thyroid di...
1/3 I have to refresh my memory from time to time about the relationship between creatine (Cr), creatine kinase (CK) and creatinine. As a hematologist, I traffic in all the above...
1/3 I saw a very interesting case recently. 22 yo M - previously well - collapsed while running a half marathon. In ED, found to have rectal Temp 40.2 degrees C and heart rate...