Avraham Z. Cooper, MD 🩺
Pulm/Crit physician and PD @OSUPCCM_Fellows • Podcast @curiousclinpod • Dad/husband • FORTHCOMING BOOK: WHY DOESN’T YOUR STOMACH DIGEST ITSELF? (W.W. Norton)
View on 𝕏Threads
1/THREAD Why would adenosine, a purine nucleoside, be able to treat supraventricular tachycardias (SVT)? And why are its effects so short lived (e.g.
1/🧵 Why is a ketogenic diet a potentially effective treatment for refractory epilepsy? There's something almost magical about the idea that a specific type of diet could reduce th...
1/🧵 Ever wonder why tick bites can lead to a red meat allergy, including even anaphylaxis? The answer requires us to examine sugars, tick saliva, and an anti-cancer drug. #medtwi...
1/ 🧵 Clostridioides difficile (C. Diff) colitis is exceedingly rare in infants, almost as if they're protected from it. But why would infants somehow be resistant to C. diff infec...
1/🧵 Ever wonder why rheumatic heart disease almost always damages heart valves? And why is the mitral valve by far the most commonly affected? The answer involves a case of mist...
1/🧵 Ever wonder why corticosteroids like dexamethasone treat cerebral edema related to brain tumors? I assumed the answer involved "anti-inflammatory effects", but there's much mo...
1/🧵 Why does chronic alcohol use cause macrocytosis? Alcohol's ability to enlarge red blood cells (RBCs) has puzzled me ever since I learned about this association, but assumed i...
1/🧵 Did you know that heparin can cause hyperkalemia? But why would an anticoagulant like heparin increase serum K⁺ levels? The answer also has a wild implication - that heparin...
1/🧵 Why does Wenckebach AV nodal block (aka Mobitz type 1) present with progressive prolongation of the PR interval and eventually a non-conducted P wave? What causes this uniqu...
1/🧵 This is the incredible story of an anesthesiologist who, in 1946, purposefully paralyzed himself using curare. Though conditions were controlled, by the end of the experiment...
1/🧵 Ever wonder why severe hypertriglyceridemia causes acute pancreatitis? Are triglycerides themselves toxic to the pancreas or is there something else going on? #tweetorial #m...
1/ 🧵 Why can propofol infusion at high doses cause Propofol-related Infusion Syndrome (PRIS)? To understand why we have to revisit the old adage of supply and demand. #Tweetoria...